BDBM50160869 CHEMBL3786398
SMILES: CC(C)C[C@@H](NC(=O)CC(NC(=O)[C@H]1CCCc2ccccc12)c1cccc(F)c1)B(O)O
InChI Key: InChIKey=GVCLUQUSDQUHGE-OCESARCHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
20S proteasome chymotrypsin-like (Homo sapiens (Human)) | BDBM50160869 (CHEMBL3786398) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair |