BDBM50160908 CHEMBL182623::{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-hydroxy-acetonitrile
SMILES: OC(C#N)c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1
InChI Key: InChIKey=SXDFNJNZJPSKSR-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50160908 (CHEMBL182623 | {5-[3-(2-Benzyloxy-5-chloro-phenyl)...) | KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against Prostaglandin E receptor was determined in human | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50160908 (CHEMBL182623 | {5-[3-(2-Benzyloxy-5-chloro-phenyl)...) | KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against Prostaglandin E receptor in presence of 2% human serum albumin | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50160908 (CHEMBL182623 | {5-[3-(2-Benzyloxy-5-chloro-phenyl)...) | GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Binding affinity against human Prostanoid TP receptor | Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV | |||||||||||
More data for this Ligand-Target Pair |