BDBM50160916 2-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-yl]-pyridin-3-yl}-1,1,1,3,3,3-hexafluoro-propan-2-ol::CHEMBL182367

SMILES: OC(c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=AJGJMWUDDSWHOG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50160916 (2-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-y...) Show SMILES OC(c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H16ClF6NO2S/c26-18-6-7-21(35-14-15-4-2-1-3-5-15)20(11-18)19-8-9-36-22(19)16-10-17(13-33-12-16)23(34,24(27,28)29)25(30,31)32/h1-13,34H,14H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity against human Prostanoid TP receptor				Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50160916 (2-{5-[3-(2-Benzyloxy-5-chloro-phenyl)-thiophen-2-y...) Show SMILES OC(c1cncc(c1)-c1sccc1-c1cc(Cl)ccc1OCc1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H16ClF6NO2S/c26-18-6-7-21(35-14-15-4-2-1-3-5-15)20(11-18)19-8-9-36-22(19)16-10-17(13-33-12-16)23(34,24(27,28)29)25(30,31)32/h1-13,34H,14H2	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity against Prostaglandin E receptor was determined in human				Bioorg Med Chem Lett 15: 1155-60 (2005) Article DOI: 10.1016/j.bmcl.2004.12.005 BindingDB Entry DOI: 10.7270/Q2SF2VNV
					More data for this Ligand-Target Pair