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SMILES: Cc1cccc(NC(=O)c2cccc(Br)n2)n1

InChI Key: InChIKey=IQNMCFJVBQJVNL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161020   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50161020
PNG
(6-Bromo-pyridine-2-carboxylic acid (6-methyl-pyrid...)
Show SMILES Cc1cccc(NC(=O)c2cccc(Br)n2)n1
Show InChI InChI=1S/C12H10BrN3O/c1-8-4-2-7-11(14-8)16-12(17)9-5-3-6-10(13)15-9/h2-7H,1H3,(H,14,16,17)
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n/an/a 21n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against human recombinant metabotropic glutamate receptor 5 (mGlu5) in Ltk cells determined using fluorescence detection met...

Bioorg Med Chem Lett 15: 1197-200 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.078
BindingDB Entry DOI: 10.7270/Q28G8K6P
More data for this
Ligand-Target Pair