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SMILES: Cc1cccc(NC(=O)c2nc(C)ccc2Nc2cccnc2)n1

InChI Key: InChIKey=OZWWGORJEFGSDB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161022   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50161022
PNG
(6-Methyl-3-(pyridin-3-ylamino)-pyridine-2-carboxyl...)
Show SMILES Cc1cccc(NC(=O)c2nc(C)ccc2Nc2cccnc2)n1
Show InChI InChI=1S/C18H17N5O/c1-12-5-3-7-16(20-12)23-18(24)17-15(9-8-13(2)21-17)22-14-6-4-10-19-11-14/h3-11,22H,1-2H3,(H,20,23,24)
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n/an/a 11n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against human recombinant metabotropic glutamate receptor 5 (mGlu5) in Ltk cells determined using fluorescence detection met...

Bioorg Med Chem Lett 15: 1197-200 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.078
BindingDB Entry DOI: 10.7270/Q28G8K6P
More data for this
Ligand-Target Pair