BDBM50161121 4-(4-Bromo-2,5-dichloro-thiophene-3-sulfonylaminocarbonyl)-piperidine-1-carboxylic acid tert-butyl ester::CHEMBL178944

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NS(=O)(=O)c1c(Cl)sc(Cl)c1Br

InChI Key: InChIKey=CFXTWGZJLHATNP-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steryl-sulfatase (Homo sapiens (Human))	BDBM50161121 (4-(4-Bromo-2,5-dichloro-thiophene-3-sulfonylaminoc...) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NS(=O)(=O)c1c(Cl)sc(Cl)c1Br Show InChI InChI=1S/C15H19BrCl2N2O5S2/c1-15(2,3)25-14(22)20-6-4-8(5-7-20)13(21)19-27(23,24)10-9(16)11(17)26-12(10)18/h8H,4-7H2,1-3H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibitory constant against human Steroid sulfatase				Bioorg Med Chem Lett 15: 1235-8 (2005) Article DOI: 10.1016/j.bmcl.2004.11.069 BindingDB Entry DOI: 10.7270/Q2RF5THG
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50161121 (4-(4-Bromo-2,5-dichloro-thiophene-3-sulfonylaminoc...) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NS(=O)(=O)c1c(Cl)sc(Cl)c1Br Show InChI InChI=1S/C15H19BrCl2N2O5S2/c1-15(2,3)25-14(22)20-6-4-8(5-7-20)13(21)19-27(23,24)10-9(16)11(17)26-12(10)18/h8H,4-7H2,1-3H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibitory concentration against human steroid sulfatase				Bioorg Med Chem Lett 15: 1235-8 (2005) Article DOI: 10.1016/j.bmcl.2004.11.069 BindingDB Entry DOI: 10.7270/Q2RF5THG
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50161121 (4-(4-Bromo-2,5-dichloro-thiophene-3-sulfonylaminoc...) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NS(=O)(=O)c1c(Cl)sc(Cl)c1Br Show InChI InChI=1S/C15H19BrCl2N2O5S2/c1-15(2,3)25-14(22)20-6-4-8(5-7-20)13(21)19-27(23,24)10-9(16)11(17)26-12(10)18/h8H,4-7H2,1-3H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibitory concentration against human steroid sulfatase expressed in CHO cells				Bioorg Med Chem Lett 15: 1235-8 (2005) Article DOI: 10.1016/j.bmcl.2004.11.069 BindingDB Entry DOI: 10.7270/Q2RF5THG
					More data for this Ligand-Target Pair