BDBM50161145 CHEMBL3793667

SMILES: OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1cccc(Cl)c1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=QHVMIYPLDXVSCM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50161145 (CHEMBL3793667) Show SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1cccc(Cl)c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11ClF9NO3S/c18-11-2-1-3-13(8-11)32(30,31)28(9-14(19,20)21)12-6-4-10(5-7-12)15(29,16(22,23)24)17(25,26)27/h1-8,29H,9H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Curated by ChEMBL					Assay Description Inverse agonist activity at recombinant human GST-tagged ROR-gamma receptor ligand binding domain assessed as inhibition of receptor and co-activator...				Bioorg Med Chem Lett 26: 2459-63 (2016) BindingDB Entry DOI: 10.7270/Q2QC05DC
					More data for this Ligand-Target Pair