BDBM50161156 CHEMBL3793914
SMILES: Cn1ccc2c(cccc12)S(=O)(=O)N(CC(F)(F)F)c1ccc2N(CCCc2c1)C(=O)c1cccs1
InChI Key: InChIKey=YDBHDGOTVMHOQG-RDJZCZTQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human)) | BDBM50161156 (CHEMBL3793914) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Curated by ChEMBL | Assay Description Inverse agonist activity at recombinant human GST-tagged ROR-gamma receptor ligand binding domain assessed as inhibition of receptor and co-activator... | Bioorg Med Chem Lett 26: 2459-63 (2016) BindingDB Entry DOI: 10.7270/Q2QC05DC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |