BDBM50161234 CHEMBL425143::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-4-pyridin-4-yl-benzamide

SMILES: Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3ccncc3)CC2)c1Cl

InChI Key: InChIKey=JXBCWOBRVYSONW-OWOJBTEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50161234 (CHEMBL425143 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...) Show SMILES Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3ccncc3)CC2)c1Cl Show InChI InChI=1S/C26H26Cl2N4O/c27-23-4-3-5-24(25(23)28)32-18-16-31(17-19-32)15-2-1-12-30-26(33)22-8-6-20(7-9-22)21-10-13-29-14-11-21/h1-11,13-14H,12,15-19H2,(H,30,33)/b2-1+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity for human dopamine D3 receptor				J Med Chem 48: 839-48 (2005) Article DOI: 10.1021/jm049465g BindingDB Entry DOI: 10.7270/Q27H1J4R
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50161234 (CHEMBL425143 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...) Show SMILES Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3ccncc3)CC2)c1Cl Show InChI InChI=1S/C26H26Cl2N4O/c27-23-4-3-5-24(25(23)28)32-18-16-31(17-19-32)15-2-1-12-30-26(33)22-8-6-20(7-9-22)21-10-13-29-14-11-21/h1-11,13-14H,12,15-19H2,(H,30,33)/b2-1+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity for human dopamine D2 receptor				J Med Chem 48: 839-48 (2005) Article DOI: 10.1021/jm049465g BindingDB Entry DOI: 10.7270/Q27H1J4R
					More data for this Ligand-Target Pair