null
SMILES: CC(C)C[C@H](NC(=O)c1ccc(cc1)N(C)C)C(=O)N1OCC2[C@H]1C(=O)CN2C(=O)c1ccccc1
InChI Key: InChIKey=SRHXJKCCOBQAOP-WKJLPXBYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin K (Homo sapiens (Human)) | BDBM50161334 (N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amura Therapeutics Limited, Inc Curated by ChEMBL | Assay Description Binding affinity against human cathepsin K | Bioorg Med Chem Lett 15: 1327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.01.022 BindingDB Entry DOI: 10.7270/Q2SB46HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine proteinase B (Leishmania mexicana) | BDBM50161334 (N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amura Therapeutics Limited, Inc Curated by ChEMBL | Assay Description Binding affinity against Leishmania mexicana cysteine peptidase B (CPB) | Bioorg Med Chem Lett 15: 1327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.01.022 BindingDB Entry DOI: 10.7270/Q2SB46HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50161334 (N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amura Therapeutics Limited, Inc Curated by ChEMBL | Assay Description Binding affinity against cruzaine | Bioorg Med Chem Lett 15: 1327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.01.022 BindingDB Entry DOI: 10.7270/Q2SB46HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin S (Homo sapiens (Human)) | BDBM50161334 (N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amura Therapeutics Limited, Inc Curated by ChEMBL | Assay Description Binding affinity against cathepsin S | Bioorg Med Chem Lett 15: 1327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.01.022 BindingDB Entry DOI: 10.7270/Q2SB46HX | |||||||||||
More data for this Ligand-Target Pair |