BDBM50161424 CHEMBL181137::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinoxalin-2-yl-methanone

SMILES: CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnc2ccccc2n1

InChI Key: InChIKey=PWPDGEOZCXYNKM-NIYFSFCBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161424 (CHEMBL181137 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...) Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnc2ccccc2n1 Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-8-19(26)14-18-6-7-21(28)22(29)15-18)20-9-12-32(13-10-20)27(34)25-16-30-23-4-2-3-5-24(23)31-25/h2-7,15-16,19-20,26H,8-14,17H2,1H3/t19-,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair