BDBM50161433 CHEMBL441848::[(3S,4S)-4-(3,4-Dichloro-benzyl)-3-methoxy-[1,4'']bipiperidinyl-1''-yl]-quinoxalin-6-yl-methanone

SMILES: CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2nccnc2c1

InChI Key: InChIKey=IMCGOKASJNONCI-NIYFSFCBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50161433 (CHEMBL441848 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...) Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2nccnc2c1 Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-6-19(26)14-18-2-4-22(28)23(29)15-18)21-7-12-32(13-8-21)27(34)20-3-5-24-25(16-20)31-10-9-30-24/h2-5,9-10,15-16,19,21,26H,6-8,11-14,17H2,1H3/t19-,26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line				Bioorg Med Chem Lett 15: 1375-8 (2005) Article DOI: 10.1016/j.bmcl.2005.01.016 BindingDB Entry DOI: 10.7270/Q2B857NS
					More data for this Ligand-Target Pair