BDBM50161576 4,5-Bis-(4-chloro-phenyl)-1-methyl-1H-imidazole-2-carboxylic acid tert-butylamide::CHEMBL181818

SMILES: Cn1c(nc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NC(C)(C)C

InChI Key: InChIKey=KSOFDKXGGLAUJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50161576 (4,5-Bis-(4-chloro-phenyl)-1-methyl-1H-imidazole-2-...) Show SMILES Cn1c(nc(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NC(C)(C)C Show InChI InChI=1S/C21H21Cl2N3O/c1-21(2,3)25-20(27)19-24-17(13-5-9-15(22)10-6-13)18(26(19)4)14-7-11-16(23)12-8-14/h5-12H,1-4H3,(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human recombinant cannabinoid receptor type 1 expressed in Chinese Hamster Ovary (CHO) cells				Bioorg Med Chem Lett 15: 1441-6 (2005) Article DOI: 10.1016/j.bmcl.2004.12.078 BindingDB Entry DOI: 10.7270/Q2F18Z7R
					More data for this Ligand-Target Pair