BDBM50161654 CHEMBL3787515

SMILES: CC(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12

InChI Key: InChIKey=RVKXRPPXPZEAMZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50161654 (CHEMBL3787515) Show SMILES CC(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12 |r| Show InChI InChI=1S/C12H23NO7/c14-4-2-1-3-9(16)13-5-7-10(17)12(19)11(18)8(6-15)20-7/h7-8,10-12,14-15,17-19H,1-6H2,(H,13,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method				Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50161654 (CHEMBL3787515) Show SMILES CC(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12 |r| Show InChI InChI=1S/C12H23NO7/c14-4-2-1-3-9(16)13-5-7-10(17)12(19)11(18)8(6-15)20-7/h7-8,10-12,14-15,17-19H,1-6H2,(H,13,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method				Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP
					More data for this Ligand-Target Pair