BDBM50161655 CHEMBL3785403
SMILES: NC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)n1cc(Cc2ccc(cc2)C2CC2)c2c(Cl)cccc12
InChI Key: InChIKey=SWJOEFJDQJHSFK-PFKOEMKTSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50161655 (CHEMBL3785403) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 237 | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method | Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human)) | BDBM50161655 (CHEMBL3785403) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG uptake after 120 mins by scintillation counting method | Bioorg Med Chem 24: 2242-50 (2016) BindingDB Entry DOI: 10.7270/Q25D8TQP | |||||||||||
More data for this Ligand-Target Pair |