BDBM50161695 1-(4-Bromo-3-fluoro-phenyl)-3-(5-chloro-thiazol-2-yl)-1-cyclopentylmethyl-urea::CHEMBL541979

SMILES: Fc1cc(ccc1Br)N(CC1CCCC1)C(=O)Nc1ncc(Cl)s1

InChI Key: InChIKey=HRGVCRHMRCEHHT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase type IV (Rattus norvegicus)	BDBM50161695 (1-(4-Bromo-3-fluoro-phenyl)-3-(5-chloro-thiazol-2-...) Show SMILES Fc1cc(ccc1Br)N(CC1CCCC1)C(=O)Nc1ncc(Cl)s1 Show InChI InChI=1S/C16H16BrClFN3OS/c17-12-6-5-11(7-13(12)19)22(9-10-3-1-2-4-10)16(23)21-15-20-8-14(18)24-15/h5-8,10H,1-4,9H2,(H,20,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
OSI Pharmaceuticals Curated by ChEMBL					Assay Description Effective concentration for glucokinase activation with 5 mM glucose				Bioorg Med Chem Lett 15: 1501-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.083 BindingDB Entry DOI: 10.7270/Q2HT2NVC
					More data for this Ligand-Target Pair