BDBM50161747 3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]-1,2,3,4-tetrahydro-carbazol-9-yl}-propionic acid::CHEMBL373118

SMILES: CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=XKWVLGMVINJGLP-MRXNPFEDSA-N

Data: 3 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50161747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptor				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptor				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of PGD2-induced inositol phosphate formation at human Prostaglandin D2 receptor				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of beta-arrestin translocation at human Thromboxane A2 receptor in BRET assay				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assay				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50161747 (3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...) Show SMILES CN([C@@H]1CCc2c(C1)c1ccccc1n2CCC(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C22H23FN2O4S/c1-24(30(28,29)17-9-6-15(23)7-10-17)16-8-11-21-19(14-16)18-4-2-3-5-20(18)25(21)13-12-22(26)27/h2-7,9-10,16H,8,11-14H2,1H3,(H,26,27)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cells				J Med Chem 48: 897-900 (2005) Article DOI: 10.1021/jm049036i BindingDB Entry DOI: 10.7270/Q24J0DMD
					More data for this Ligand-Target Pair