BDBM50162057 (+)2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(-)2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::CHEMBL369147

SMILES: Ic1cncc(c1)C1CC2CCC1N2

InChI Key: InChIKey=IVUVTGPUTWVVQB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50162057 ((+)2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hep...) Show SMILES Ic1cncc(c1)C1CC2CCC1N2 |THB:5:7:13:11.10| Show InChI InChI=1S/C11H13IN2/c12-8-3-7(5-13-6-8)10-4-9-1-2-11(10)14-9/h3,5-6,9-11,14H,1-2,4H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex				J Med Chem 48: 1221-8 (2005) Article DOI: 10.1021/jm040160b BindingDB Entry DOI: 10.7270/Q26W9BV6
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50162057 ((+)2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hep...) Show SMILES Ic1cncc(c1)C1CC2CCC1N2 |THB:5:7:13:11.10| Show InChI InChI=1S/C11H13IN2/c12-8-3-7(5-13-6-8)10-4-9-1-2-11(10)14-9/h3,5-6,9-11,14H,1-2,4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-iodo-MLA binding to Nicotinic acetylcholine receptor alpha-7 in rat cerebral cortex				J Med Chem 48: 1221-8 (2005) Article DOI: 10.1021/jm040160b BindingDB Entry DOI: 10.7270/Q26W9BV6
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50162057 ((+)2-(5-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hep...) Show SMILES Ic1cncc(c1)C1CC2CCC1N2 |THB:5:7:13:11.10| Show InChI InChI=1S/C11H13IN2/c12-8-3-7(5-13-6-8)10-4-9-1-2-11(10)14-9/h3,5-6,9-11,14H,1-2,4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [125I]-iodo-MLA binding to Nicotinic acetylcholine receptor alpha-7 in rat cerebral cortex				J Med Chem 48: 1221-8 (2005) Article DOI: 10.1021/jm040160b BindingDB Entry DOI: 10.7270/Q26W9BV6
					More data for this Ligand-Target Pair