BDBM50162366 CHEMBL193850::[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethyl]-[2-(2-methoxy-phenyl)-ethyl]-amine

SMILES: COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=GKLOYHIRKOCPMO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50162366 (CHEMBL193850 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...) Show SMILES COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H38F3N3O/c1-35-27-10-6-5-7-23(27)15-16-32-21-26(22-11-13-24(14-12-22)28(29,30)31)34-19-17-33(18-20-34)25-8-3-2-4-9-25/h5-7,10-14,25-26,32H,2-4,8-9,15-21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biographics Laboratory 3R Curated by ChEMBL					Assay Description Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)				J Med Chem 48: 1515-27 (2005) Article DOI: 10.1021/jm040827u BindingDB Entry DOI: 10.7270/Q2KK9B8W
					More data for this Ligand-Target Pair