BDBM50162542 2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one::CHEMBL180336
SMILES: O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccco1
InChI Key: InChIKey=ZFIMKOHGGKYLGR-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium-sensing receptor (CaSR) (Homo sapiens (Human)) | BDBM50162542 (2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptor | Bioorg Med Chem Lett 15: 2537-40 (2005) Article DOI: 10.1016/j.bmcl.2005.03.054 BindingDB Entry DOI: 10.7270/Q26Q1WRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium-sensing receptor (CaSR) (Homo sapiens (Human)) | BDBM50162542 (2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD | |||||||||||
More data for this Ligand-Target Pair |