BDBM50162547 3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)-5-methyl-3H-quinazolin-4-one::CHEMBL360226

SMILES: Cc1cccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c12

InChI Key: InChIKey=SVQGUGCDMVTZMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50162547 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Cc1cccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c12 Show InChI InChI=1S/C23H19FN2O2/c1-15-6-4-10-19-21(15)23(28)26(13-12-16-7-5-8-17(24)14-16)22(25-19)18-9-2-3-11-20(18)27/h2-11,14,27H,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair