BDBM50162552 7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-one::CHEMBL361316

SMILES: Oc1ccccc1-c1nc2cc(F)ccc2c(=O)n1CCc1ccccc1

InChI Key: InChIKey=KWHYVBAASFOQKW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50162552 (7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Oc1ccccc1-c1nc2cc(F)ccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H17FN2O2/c23-16-10-11-17-19(14-16)24-21(18-8-4-5-9-20(18)26)25(22(17)27)13-12-15-6-2-1-3-7-15/h1-11,14,26H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair