BDBM50162554 2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-one::2-(2-hydroxyphenyl)-3-phenethylquinazolin-4(3H)-one::CHEMBL180030

SMILES: Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1

InChI Key: InChIKey=VQTHMGSYEABTGU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50162554 (2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O2/c25-20-13-7-5-11-18(20)21-23-19-12-6-4-10-17(19)22(26)24(21)15-14-16-8-2-1-3-9-16/h1-13,25H,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of CaSR				J Med Chem 53: 4332-53 (2010) Article DOI: 10.1021/jm9018756 BindingDB Entry DOI: 10.7270/Q21R6QPF
					More data for this Ligand-Target Pair
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50162554 (2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI InChI=1S/C22H18N2O2/c25-20-13-7-5-11-18(20)21-23-19-12-6-4-10-17(19)22(26)24(21)15-14-16-8-2-1-3-9-16/h1-13,25H,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
					More data for this Ligand-Target Pair