BDBM50162556 6,7-Dichloro-2-isopropyl-5-[3-(pyridin-4-ylsulfanylmethyl)-benzyloxy]-indan-1-one::CHEMBL179171
SMILES: CC(C)C1Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(Cl)c(Cl)c2C1=O
InChI Key: InChIKey=JTZQHJFWRXNBEQ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50162556 (6,7-Dichloro-2-isopropyl-5-[3-(pyridin-4-ylsulfany...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 839 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity against metabotropic glutamate receptor 2 | Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK | |||||||||||
More data for this Ligand-Target Pair |