BDBM50162558 6,7-Dichloro-2-cyclopentyl-2-methyl-5-{4-[4-(2H-tetrazol-5-yl)-phenoxy]-butoxy}-indan-1-one::CHEMBL361837
SMILES: CC1(Cc2cc(OCCCCOc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1
InChI Key: InChIKey=FPPKJNIYDBNWAJ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50162558 (6,7-Dichloro-2-cyclopentyl-2-methyl-5-{4-[4-(2H-te...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 225 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity against metabotropic glutamate receptor 2 | Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK | |||||||||||
More data for this Ligand-Target Pair |