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BDBM50162558 6,7-Dichloro-2-cyclopentyl-2-methyl-5-{4-[4-(2H-tetrazol-5-yl)-phenoxy]-butoxy}-indan-1-one::CHEMBL361837

SMILES: CC1(Cc2cc(OCCCCOc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=FPPKJNIYDBNWAJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162558   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50162558
PNG
(6,7-Dichloro-2-cyclopentyl-2-methyl-5-{4-[4-(2H-te...)
Show SMILES CC1(Cc2cc(OCCCCOc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1
Show InChI InChI=1S/C26H28Cl2N4O3/c1-26(18-6-2-3-7-18)15-17-14-20(22(27)23(28)21(17)24(26)33)35-13-5-4-12-34-19-10-8-16(9-11-19)25-29-31-32-30-25/h8-11,14,18H,2-7,12-13,15H2,1H3,(H,29,30,31,32)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 225n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 15: 1565-71 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.077
BindingDB Entry DOI: 10.7270/Q2XW4JBK
More data for this
Ligand-Target Pair