BDBM50162559 6,7-Dimethyl-2-propyl-5-[3-(pyridin-4-ylsulfanylmethyl)-benzyloxy]-indan-1-one::CHEMBL180871

SMILES: CCCC1Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(C)c(C)c2C1=O

InChI Key: InChIKey=ZLGWVGNNHFSKSO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50162559 (6,7-Dimethyl-2-propyl-5-[3-(pyridin-4-ylsulfanylme...) Show SMILES CCCC1Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(C)c(C)c2C1=O Show InChI InChI=1S/C27H29NO2S/c1-4-6-22-14-23-15-25(18(2)19(3)26(23)27(22)29)30-16-20-7-5-8-21(13-20)17-31-24-9-11-28-12-10-24/h5,7-13,15,22H,4,6,14,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	291	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against metabotropic glutamate receptor 2				Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK
					More data for this Ligand-Target Pair