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BDBM50162561 6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(2H-tetrazol-5-yl)-propoxy]-indan-1-one::CHEMBL182138

SMILES: CC1(Cc2cc(OCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=UOJKSVVDYDTODM-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162561   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50162561
PNG
(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(2H-tetra...)
Show SMILES CC1(Cc2cc(OCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1
Show InChI InChI=1S/C19H22Cl2N4O2/c1-19(12-5-2-3-6-12)10-11-9-13(16(20)17(21)15(11)18(19)26)27-8-4-7-14-22-24-25-23-14/h9,12H,2-8,10H2,1H3,(H,22,23,24,25)
PDB

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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 5.00E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 15: 1565-71 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.077
BindingDB Entry DOI: 10.7270/Q2XW4JBK
More data for this
Ligand-Target Pair