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BDBM50162562 6,7-Dichloro-2-methyl-2-phenyl-5-[4-(2H-tetrazol-5-yl)-benzyloxy]-indan-1-one::CHEMBL361633

SMILES: CC1(Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)c1ccccc1

InChI Key: InChIKey=ZKZXTORBDBMWLL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50162562
PNG
(6,7-Dichloro-2-methyl-2-phenyl-5-[4-(2H-tetrazol-5...)
Show SMILES CC1(Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)c1ccccc1
Show InChI InChI=1S/C24H18Cl2N4O2/c1-24(17-5-3-2-4-6-17)12-16-11-18(20(25)21(26)19(16)22(24)31)32-13-14-7-9-15(10-8-14)23-27-29-30-28-23/h2-11H,12-13H2,1H3,(H,27,28,29,30)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 629n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 15: 1565-71 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.077
BindingDB Entry DOI: 10.7270/Q2XW4JBK
More data for this
Ligand-Target Pair