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BDBM50162564 6,7-Dichloro-2-cyclopentyl-2-methyl-5-[4-(2H-tetrazol-5-yl)-butoxy]-indan-1-one::CHEMBL183234

SMILES: CC1(Cc2cc(OCCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=QYCMOMQQQZLZJM-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162564   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50162564
PNG
(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[4-(2H-tetra...)
Show SMILES CC1(Cc2cc(OCCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1
Show InChI InChI=1S/C20H24Cl2N4O2/c1-20(13-6-2-3-7-13)11-12-10-14(17(21)18(22)16(12)19(20)27)28-9-5-4-8-15-23-25-26-24-15/h10,13H,2-9,11H2,1H3,(H,23,24,25,26)
PDB

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PC sid
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Patents

Article
PubMed
n/an/an/an/a 589n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against metabotropic glutamate receptor 2


Bioorg Med Chem Lett 15: 1565-71 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.077
BindingDB Entry DOI: 10.7270/Q2XW4JBK
More data for this
Ligand-Target Pair