BDBM50162570 2-(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yloxy)-N-[4-(2H-tetrazol-5-yl)-phenyl]-acetamide::CHEMBL361358

SMILES: CC1(Cc2cc(OCC(=O)Nc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=RBWXCWNWUNBVQW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50162570 (2-(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-indan...) Show SMILES CC1(Cc2cc(OCC(=O)Nc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1 Show InChI InChI=1S/C24H23Cl2N5O3/c1-24(15-4-2-3-5-15)11-14-10-17(20(25)21(26)19(14)22(24)33)34-12-18(32)27-16-8-6-13(7-9-16)23-28-30-31-29-23/h6-10,15H,2-5,11-12H2,1H3,(H,27,32)(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against metabotropic glutamate receptor 2				Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK
					More data for this Ligand-Target Pair