BDBM50162575 6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(pyridin-4-ylsulfanylmethyl)-benzyloxy]-indan-1-one::CHEMBL179876

SMILES: CC1(Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=XOQQXEHVSQPOKL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50162575 (6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(pyridin-...) Show SMILES CC1(Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(Cl)c(Cl)c2C1=O)C1CCCC1 Show InChI InChI=1S/C28H27Cl2NO2S/c1-28(21-7-2-3-8-21)15-20-14-23(25(29)26(30)24(20)27(28)32)33-16-18-5-4-6-19(13-18)17-34-22-9-11-31-12-10-22/h4-6,9-14,21H,2-3,7-8,15-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against metabotropic glutamate receptor 2				Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK
					More data for this Ligand-Target Pair