BDBM50162578 6,7-Dichloro-2,2-dimethyl-5-[4-(2H-tetrazol-5-yl)-benzyloxy]-indan-1-one::CHEMBL180488

SMILES: CC1(C)Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O

InChI Key: InChIKey=XIXNRVYHFCYTSQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50162578 (6,7-Dichloro-2,2-dimethyl-5-[4-(2H-tetrazol-5-yl)-...) Show SMILES CC1(C)Cc2cc(OCc3ccc(cc3)-c3nnn[nH]3)c(Cl)c(Cl)c2C1=O Show InChI InChI=1S/C19H16Cl2N4O2/c1-19(2)8-12-7-13(15(20)16(21)14(12)17(19)26)27-9-10-3-5-11(6-4-10)18-22-24-25-23-18/h3-7H,8-9H2,1-2H3,(H,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	782	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against metabotropic glutamate receptor 2				Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK
					More data for this Ligand-Target Pair