BDBM50162580 6,7-Dichloro-2-cyclopentyl-2-methyl-5-[5-(2H-tetrazol-5-yl)-pentyloxy]-indan-1-one::CHEMBL183286

SMILES: CC1(Cc2cc(OCCCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1

InChI Key: InChIKey=OMDAXCSLKUCCJH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50162580 (6,7-Dichloro-2-cyclopentyl-2-methyl-5-[5-(2H-tetra...) Show SMILES CC1(Cc2cc(OCCCCCc3nnn[nH]3)c(Cl)c(Cl)c2C1=O)C1CCCC1 Show InChI InChI=1S/C21H26Cl2N4O2/c1-21(14-7-4-5-8-14)12-13-11-15(18(22)19(23)17(13)20(21)28)29-10-6-2-3-9-16-24-26-27-25-16/h11,14H,2-10,12H2,1H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	761	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against metabotropic glutamate receptor 2				Bioorg Med Chem Lett 15: 1565-71 (2005) Article DOI: 10.1016/j.bmcl.2005.01.077 BindingDB Entry DOI: 10.7270/Q2XW4JBK
					More data for this Ligand-Target Pair