BDBM50162786 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzamide::CHEMBL360148

SMILES: CC(C(c1ccc2cc(OCc3cccc(c3)C(N)=O)ccc2c1)n1ccnc1)N(C)C

InChI Key: InChIKey=GNOBXZHCXJWOKL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50162786 (3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...) Show SMILES CC(C(c1ccc2cc(OCc3cccc(c3)C(N)=O)ccc2c1)n1ccnc1)N(C)C Show InChI InChI=1S/C26H28N4O2/c1-18(29(2)3)25(30-12-11-28-17-30)22-8-7-21-15-24(10-9-20(21)14-22)32-16-19-5-4-6-23(13-19)26(27)31/h4-15,17-18,25H,16H2,1-3H3,(H2,27,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Potency towards cytochrome P 450 26 enzyme activity				Bioorg Med Chem Lett 15: 1669-73 (2005) Article DOI: 10.1016/j.bmcl.2005.01.044 BindingDB Entry DOI: 10.7270/Q2WW7H5R
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50162786 (3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...) Show SMILES CC(C(c1ccc2cc(OCc3cccc(c3)C(N)=O)ccc2c1)n1ccnc1)N(C)C Show InChI InChI=1S/C26H28N4O2/c1-18(29(2)3)25(30-12-11-28-17-30)22-8-7-21-15-24(10-9-20(21)14-22)32-16-19-5-4-6-23(13-19)26(27)31/h4-15,17-18,25H,16H2,1-3H3,(H2,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Selectivity towards cytochrome P450 3A4 enzyme activity				Bioorg Med Chem Lett 15: 1669-73 (2005) Article DOI: 10.1016/j.bmcl.2005.01.044 BindingDB Entry DOI: 10.7270/Q2WW7H5R
					More data for this Ligand-Target Pair