BDBM50162911 3-[6-(3,4-Difluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid::CHEMBL180258
SMILES: OC(=O)CCn1c2CCCCc2c2cc(NS(=O)(=O)c3ccc(F)c(F)c3)ccc12
InChI Key: InChIKey=MTCGMIAUIWBKOZ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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G protein-coupled receptor 44 (Homo sapiens (Human)) | BDBM50162911 (3-[6-(3,4-Difluoro-benzenesulfonylamino)-1,2,3,4-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes | Bioorg Med Chem Lett 15: 1749-53 (2005) Article DOI: 10.1016/j.bmcl.2004.12.055 BindingDB Entry DOI: 10.7270/Q20P0ZHT | |||||||||||
More data for this Ligand-Target Pair |