BDBM50163247 2-[3-(3,4-Dichloro-phenoxy)-phenyl]-1H-benzoimidazole-5-carboxylic acid amide::CHEMBL175676

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1cccc(Oc2ccc(Cl)c(Cl)c2)c1

InChI Key: InChIKey=YBVHQGCYILOKSG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163247 (2-[3-(3,4-Dichloro-phenoxy)-phenyl]-1H-benzoimidaz...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1cccc(Oc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C20H13Cl2N3O2/c21-15-6-5-14(10-16(15)22)27-13-3-1-2-12(8-13)20-24-17-7-4-11(19(23)26)9-18(17)25-20/h1-10H,(H2,23,26)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair