BDBM50163253 2-(4-Benzyloxy-phenyl)-1H-benzoimidazole-5-carboxylic acid amide::CHEMBL192022

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=HCPHXVGNGUBXKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163253 (2-(4-Benzyloxy-phenyl)-1H-benzoimidazole-5-carboxy...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H17N3O2/c22-20(25)16-8-11-18-19(12-16)24-21(23-18)15-6-9-17(10-7-15)26-13-14-4-2-1-3-5-14/h1-12H,13H2,(H2,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair