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BDBM50163262 2-Dibenzofuran-2-yl-1H-benzoimidazole-5-carboxylic acid amide::CHEMBL195648

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc2oc3ccccc3c2c1

InChI Key: InChIKey=GJVMIPTXJYBNCN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163262   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50163262
PNG
(2-Dibenzofuran-2-yl-1H-benzoimidazole-5-carboxylic...)
Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc2oc3ccccc3c2c1
Show InChI InChI=1S/C20H13N3O2/c21-19(24)11-5-7-15-16(10-11)23-20(22-15)12-6-8-18-14(9-12)13-3-1-2-4-17(13)25-18/h1-10H,(H2,21,24)(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of recombinant human Chk2 kinase


J Med Chem 48: 1873-85 (2005)


Article DOI: 10.1021/jm0495935
BindingDB Entry DOI: 10.7270/Q2FQ9W4V
More data for this
Ligand-Target Pair