BDBM50163267 2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxylic acid dimethylamide::CHEMBL175878

SMILES: CN(C)C(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=WCRYXSBNKKJUIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163267 (2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...) Show SMILES CN(C)C(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H19N3O2/c1-25(2)22(26)16-10-13-19-20(14-16)24-21(23-19)15-8-11-18(12-9-15)27-17-6-4-3-5-7-17/h3-14H,1-2H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair