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BDBM50163286 2-(4''-Chloro-biphenyl-4-yl)-1H-benzoimidazole-5-carboxylic acid amide::CHEMBL195599

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=CBVZRVMIRYIMRV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163286   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM50163286
PNG
(2-(4''-Chloro-biphenyl-4-yl)-1H-benzoimidazole-5-c...)
Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H14ClN3O/c21-16-8-5-13(6-9-16)12-1-3-14(4-2-12)20-23-17-10-7-15(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of recombinant human Chk2 kinase


J Med Chem 48: 1873-85 (2005)


Article DOI: 10.1021/jm0495935
BindingDB Entry DOI: 10.7270/Q2FQ9W4V
More data for this
Ligand-Target Pair