BDBM50163289 2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxylic acid::2-(4-phenoxyphenyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL367390

SMILES: OC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=JZQQAMWHSMDRQY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163289 (2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...) Show SMILES OC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C20H14N2O3/c23-20(24)14-8-11-17-18(12-14)22-19(21-17)13-6-9-16(10-7-13)25-15-4-2-1-3-5-15/h1-12H,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of chk2 kinase				Bioorg Med Chem Lett 16: 1924-8 (2006) Article DOI: 10.1016/j.bmcl.2005.12.096 BindingDB Entry DOI: 10.7270/Q2XG9QPW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50163289 (2-(4-Phenoxy-phenyl)-1H-benzoimidazole-5-carboxyli...) Show SMILES OC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C20H14N2O3/c23-20(24)14-8-11-17-18(12-14)22-19(21-17)13-6-9-16(10-7-13)25-15-4-2-1-3-5-15/h1-12H,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair