BDBM50163392 CHEMBL1808018

SMILES: Cc1ccc(cc1)C(=O)c1coc2C=C(Br)C(=O)C(=O)c12

InChI Key: InChIKey=WKICJUBXSOGMSG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM50163392 (CHEMBL1808018) Show SMILES Cc1ccc(cc1)C(=O)c1coc2C=C(Br)C(=O)C(=O)c12 |t:14| Show InChI InChI=1S/C16H9BrO4/c1-8-2-4-9(5-3-8)14(18)10-7-21-12-6-11(17)15(19)16(20)13(10)12/h2-7H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs...				Bioorg Med Chem Lett 26: 2284-8 (2016) BindingDB Entry DOI: 10.7270/Q2XP76TS
					More data for this Ligand-Target Pair