BDBM50163561 CHEMBL3792511
SMILES: [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(OC1C2)[C@H](CCCC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCc2ccccc12
InChI Key: InChIKey=OLLXHMPFWVGDOS-XWRXRWDISA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
20S proteasome chymotrypsin-like (Homo sapiens (Human)) | BDBM50163561 (CHEMBL3792511) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.25E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Forestry University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs... | Bioorg Med Chem 24: 2576-88 (2016) BindingDB Entry DOI: 10.7270/Q2P84DSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
20S proteasome chymotrypsin-like (Homo sapiens (Human)) | BDBM50163561 (CHEMBL3792511) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Forestry University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs... | Bioorg Med Chem 24: 2576-88 (2016) BindingDB Entry DOI: 10.7270/Q2P84DSC | |||||||||||
More data for this Ligand-Target Pair |