BDBM50163632 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-(4-methoxy-phenyl)-urea::CHEMBL194601

SMILES: COc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1

InChI Key: InChIKey=OEKONQSOWUDFGV-AOJNWGRGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50163632 (1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...) Show SMILES COc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 Show InChI InChI=1S/C27H36FN3O2/c1-33-25-14-12-24(13-15-25)29-27(32)30-26-7-3-2-6-22(26)19-31-16-4-5-21(18-31)17-20-8-10-23(28)11-9-20/h8-15,21-22,26H,2-7,16-19H2,1H3,(H2,29,30,32)/t21-,22-,26+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of eotaxin-induced chemotaxis of human eosinophils				J Med Chem 48: 2194-211 (2005) Article DOI: 10.1021/jm049530m BindingDB Entry DOI: 10.7270/Q2XP74F1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50163632 (1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...) Show SMILES COc1ccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc1 Show InChI InChI=1S/C27H36FN3O2/c1-33-25-14-12-24(13-15-25)29-27(32)30-26-7-3-2-6-22(26)19-31-16-4-5-21(18-31)17-20-8-10-23(28)11-9-20/h8-15,21-22,26H,2-7,16-19H2,1H3,(H2,29,30,32)/t21-,22-,26+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of eotaxin-induced chemotaxis of human eosinophils				J Med Chem 48: 2194-211 (2005) Article DOI: 10.1021/jm049530m BindingDB Entry DOI: 10.7270/Q2XP74F1
					More data for this Ligand-Target Pair