BDBM50164030 (1S,2S)-Cyclopentane-1,2-dicarboxylic acid 1-[(2''-methoxy-biphenyl-4-ylmethyl)-amide] 2-[(2''-sulfamoyl-biphenyl-4-ylmethyl)-amide]::CHEMBL360962

SMILES: COc1ccccc1-c1ccc(CNC(=O)[C@H]2CCC[C@@H]2C(=O)NCc2ccc(cc2)-c2ccccc2S(N)(=O)=O)cc1

InChI Key: InChIKey=KGCWACVIVMZSMX-KYJUHHDHSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50164030 ((1S,2S)-Cyclopentane-1,2-dicarboxylic acid 1-[(2''...) Show SMILES COc1ccccc1-c1ccc(CNC(=O)[C@H]2CCC[C@@H]2C(=O)NCc2ccc(cc2)-c2ccccc2S(N)(=O)=O)cc1 Show InChI InChI=1S/C34H35N3O5S/c1-42-31-11-4-2-7-27(31)25-17-13-23(14-18-25)21-36-33(38)29-9-6-10-30(29)34(39)37-22-24-15-19-26(20-16-24)28-8-3-5-12-32(28)43(35,40)41/h2-5,7-8,11-20,29-30H,6,9-10,21-22H2,1H3,(H,36,38)(H,37,39)(H2,35,40,41)/t29-,30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)				Bioorg Med Chem Lett 15: 1901-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.002 BindingDB Entry DOI: 10.7270/Q2HH6JMD
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50164030 ((1S,2S)-Cyclopentane-1,2-dicarboxylic acid 1-[(2''...) Show SMILES COc1ccccc1-c1ccc(CNC(=O)[C@H]2CCC[C@@H]2C(=O)NCc2ccc(cc2)-c2ccccc2S(N)(=O)=O)cc1 Show InChI InChI=1S/C34H35N3O5S/c1-42-31-11-4-2-7-27(31)25-17-13-23(14-18-25)21-36-33(38)29-9-6-10-30(29)34(39)37-22-24-15-19-26(20-16-24)28-8-3-5-12-32(28)43(35,40)41/h2-5,7-8,11-20,29-30H,6,9-10,21-22H2,1H3,(H,36,38)(H,37,39)(H2,35,40,41)/t29-,30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assay				Bioorg Med Chem Lett 15: 1901-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.002 BindingDB Entry DOI: 10.7270/Q2HH6JMD
					More data for this Ligand-Target Pair