BDBM50164144 6-(2-Hydroxy-6-methoxy-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL180290

SMILES: COc1cccc(O)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key: InChIKey=XYKJPYZNOLWTGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50164144 (6-(2-Hydroxy-6-methoxy-phenyl)-8-methyl-2-phenylam...) Show SMILES COc1cccc(O)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O |(2.48,4.82,;2.5,3.28,;3.83,2.52,;5.14,3.29,;6.49,2.54,;6.49,1,;5.16,.23,;5.19,-1.31,;3.83,.98,;2.5,.21,;1.19,.97,;-.16,.19,;-1.49,.97,;-2.8,.19,;-2.8,-1.35,;-4.15,-2.12,;-5.48,-1.35,;-5.48,.19,;-6.81,.96,;-8.14,.18,;-8.14,-1.38,;-6.81,-2.13,;-1.49,-2.12,;-.16,-1.34,;1.2,-2.12,;1.2,-3.65,;2.53,-1.34,;3.86,-2.1,)| Show InChI InChI=1S/C21H18N4O3/c1-25-19-13(12-22-21(24-19)23-14-7-4-3-5-8-14)11-15(20(25)27)18-16(26)9-6-10-17(18)28-2/h3-12,26H,1-2H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair