BDBM50164145 6-(2-Chloro-6-methyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL180810

SMILES: Cc1cccc(Cl)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key: InChIKey=KEMLIWDZNMDCCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50164145 (6-(2-Chloro-6-methyl-phenyl)-8-methyl-2-phenylamin...) Show SMILES Cc1cccc(Cl)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O |(5.28,-1.15,;5.26,.4,;6.59,1.18,;6.59,2.72,;5.23,3.48,;3.93,2.7,;2.57,3.45,;3.93,1.16,;2.61,.39,;1.27,1.16,;-.06,.37,;-1.39,1.14,;-2.72,.37,;-2.72,-1.17,;-4.05,-1.94,;-5.38,-1.17,;-5.38,.37,;-6.71,1.14,;-8.04,.34,;-8.03,-1.2,;-6.71,-1.97,;-1.39,-1.94,;-.06,-1.17,;1.29,-1.94,;1.29,-3.48,;2.62,-1.15,;3.95,-1.92,)| Show InChI InChI=1S/C21H17ClN4O/c1-13-7-6-10-17(22)18(13)16-11-14-12-23-21(24-15-8-4-3-5-9-15)25-19(14)26(2)20(16)27/h3-12H,1-2H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of checkpoint kinase Wee1				Bioorg Med Chem Lett 15: 1931-5 (2005) Article DOI: 10.1016/j.bmcl.2005.01.079 BindingDB Entry DOI: 10.7270/Q280524M
					More data for this Ligand-Target Pair