BDBM50164166 CHEMBL3798933

SMILES: CCN1c2cc(ccc2C(=O)NC1(C)C)-n1c2cccnc2[nH]c1=O

InChI Key: InChIKey=GILPLWUKAXFPKQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50164166 (CHEMBL3798933) Show SMILES CCN1c2cc(ccc2C(=O)NC1(C)C)-n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C18H19N5O2/c1-4-22-14-10-11(7-8-12(14)16(24)21-18(22,2)3)23-13-6-5-9-19-15(13)20-17(23)25/h5-10H,4H2,1-3H3,(H,21,24)(H,19,20,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta in human Jurkat cells after overnight incubation by luminescence analysis				Bioorg Med Chem 24: 2466-75 (2016) Article DOI: 10.1016/j.bmc.2016.04.008 BindingDB Entry DOI: 10.7270/Q27W6F29
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50164166 (CHEMBL3798933) Show SMILES CCN1c2cc(ccc2C(=O)NC1(C)C)-n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C18H19N5O2/c1-4-22-14-10-11(7-8-12(14)16(24)21-18(22,2)3)23-13-6-5-9-19-15(13)20-17(23)25/h5-10H,4H2,1-3H3,(H,21,24)(H,19,20,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...				Bioorg Med Chem 24: 2466-75 (2016) Article DOI: 10.1016/j.bmc.2016.04.008 BindingDB Entry DOI: 10.7270/Q27W6F29
					More data for this Ligand-Target Pair