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BDBM50164218 CHEMBL192770::N-[6-(Imidazo[1,2-d][1,2,4]thiadiazol-3-ylamino)-hexyl]-3-nitro-benzenesulfonamide

SMILES: [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCCCCCNc1n[s+]c2[n-]ccn12

InChI Key: InChIKey=ZVLNLMIPMOOORI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164218   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor XIII


(Homo sapiens (Human))
BDBM50164218
PNG
(CHEMBL192770 | N-[6-(Imidazo[1,2-d][1,2,4]thiadiaz...)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCCCCCNc1n[s+]c2[n-]ccn12
Show InChI InChI=1S/C16H20N6O4S2/c23-22(24)13-6-5-7-14(12-13)28(25,26)19-9-4-2-1-3-8-17-15-20-27-16-18-10-11-21(15)16/h5-7,10-12,19H,1-4,8-9H2,(H,17,20)
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MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Apotex Research Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration of compound against factor XIIIa


J Med Chem 48: 2266-9 (2005)


Article DOI: 10.1021/jm049221w
BindingDB Entry DOI: 10.7270/Q2R210XM
More data for this
Ligand-Target Pair