BDBM50164219 CHEMBL190568::N-[6-(Imidazo[1,2-d][1,2,4]thiadiazol-3-ylamino)-hexyl]-benzenesulfonamide

SMILES: O=S(=O)(NCCCCCCNc1nsc2nccn12)c1ccccc1

InChI Key: InChIKey=DLEKJUIULJOQGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XIII (Homo sapiens (Human))	BDBM50164219 (CHEMBL190568 | N-[6-(Imidazo[1,2-d][1,2,4]thiadiaz...) Show SMILES O=S(=O)(NCCCCCCNc1nsc2nccn12)c1ccccc1 Show InChI InChI=1S/C16H21N5O2S2/c22-25(23,14-8-4-3-5-9-14)19-11-7-2-1-6-10-17-15-20-24-16-18-12-13-21(15)16/h3-5,8-9,12-13,19H,1-2,6-7,10-11H2,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Apotex Research Inc. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of compound against factor XIIIa				J Med Chem 48: 2266-9 (2005) Article DOI: 10.1021/jm049221w BindingDB Entry DOI: 10.7270/Q2R210XM
					More data for this Ligand-Target Pair